A vaccine contains an antigen, which can provoke an immune response in a human or animal so that the ability of the immune system to fight the corresponding pathogen. The vaccines may be attenuated live microorganisms, as in the MMR vaccine (mumps, measles, Rubella); inactivated microbes (bacteria or viruses); or parts of them (proteins or polysaccharides), as in the DTaP vaccine against diphtheria, tetanus and whooping cough.

High demands are placed on upstream and downstream processes both to prevent contamination and to increase the yield. A production process begins with the parent strain, which undergoes fermentation, extraction, purification, inactivation and adsorption and finally formulation and filling.

The ZETA Advantage

ZETA has wide experience and competence in design of processes and production of equipment for vaccine production. ZETA understands the needs of the vaccine manufacturers, who are under great pressure to bring new vaccines to market as quickly as possible and with the highest quality. The ZETA portfolio is completed by competences in sterile filtration, mechanical separation, fermentation, high-pressure homogenisation, fully integrated automation and batch management software.

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