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Biotech Scale-Up

Scale-up services from lab to industrial production.

We support you at all stages of your project.

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The image shows a laboratory with a large stainless steel bioreactor labeled

The image shows a clean industrial facility with two people in protective clothing standing on a blue floor. They are surrounded by stainless steel tanks, pipes, and control panels, likely in a pharmaceutical or food processing plant. One person holds a clipboard or tablet.

Smooth transitions. From concept to commercialization.

Scaling biopharmaceutical production from laboratory to industrial scale is complex – but essential for market readiness. ZETA guides biotech innovators and manufacturers through each phase of scale-up, ensuring technical, operational, and business success.

The hidden power of concept design

Concept design amounts to just 1 % of all project costs. However, 80 % of the investment costs are committed during the initiation phase of a project. A properly conducted concept design is paramount, as unfavorable decisions will have a huge impact on later phases.

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Aligning science & engineering for scalable success. Navigating the phases of scale-up with confidence.

From early-stage strain development to full-scale implementation, ZETA’s scale-up approach integrates:

Biological and process engineering expertise
Early-stage concept design to set the right course
Pilot studies to define optimal process conditions
Business case alignment for commercial viability

Our deep understanding of how biological systems behave differently at scale helps ensure your production remains robust, cost-effective, and regulatory compliant.

Lab scale

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Manual operations with small quantities – focused on strain development and basic process parameters.

Pilot scale (<50 – 200 L)

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Refines process understanding, equipment dynamics, limitations, and interdependencies.

Industrial scale

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Applies validated parameters to achieve consistent production at commercial volumes. At each phase, ZETA helps you identify scale-dependent variables, optimize utilities and energy use, and avoid costly trial-and-error.

The image shows a professional laboratory with multiple workstations, computers, scientific instruments, and shelves stocked with supplies and chemicals.

The image shows a clean, modern laboratory with a biosafety cabinet, a central table holding electronic devices and tubing setups, and various cabinets and lab equipment in the background.

The image shows a clean, high-tech industrial facility with stainless steel tanks, pipes, and control panels. A person in protective clothing is operating a touchscreen panel.

Overcoming challenges. What it takes to deliver excellence.

Comprehensive view

Providing end-to-end support with in-depth expertise.

Early-stage engineering

Ensuring the right path during the initial phases of a project to secure business profitability.

Interdisciplinary cooperation

Interlocking biological science with process and manufacturing technologies.

Pilot plant insights

Pilot scale studies are extremely important for defining optimal process conditions, and for selecting and scaling the correct technologies.

Technology upscaling

Smooth transition from pilot to industrial scale.

Developing your business case. Ensuring a profitable production system.

With ZETA as your partner, concept design isn’t just a phase – it’s your foundation.
We understand that 1% of the budget shapes 80% of investment outcomes. Our scale-up support:

Enables first-time-right design
De-risks CAPEX investment
Ensures technical feasibility aligns with economic goals

Our CAPEX project experience helps biotech firms move quickly and confidently from promising science to industrial-scale impact.

Let’s tackle your challenges together.

Get in touch Get in touch

Roland Maichin

Corporate Head of Project Development

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Downloads. Biotech scale-up.

Technical text: Early stage engineering – the key to business profitability

ZETA supports customers from the early lab phase through clinical studies and industrial-scale production, ensuring a smooth and cost-effective process by identifying risks early and leveraging profound process knowledge.