ZETA|Services|Process Optimization
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Process Optimization

Optimize your pharma and biotech process with bioreactor design, characterization, and simulation.

From black box to well-characterized bioproduction system – improving performance with expertise.
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We guide you to the optimal manufacturing process. Increasing productivity. Ensuring product quality.

Bioreactors must provide ideal conditions for cell growth and product formation – a foundation for achieving high product yield and consistent quality. Optimizing these conditions requires more than standard design. It demands expert bioreactor engineering and the precise selection of process parameters during fermentation and cultivation.

Knowing bioprocess influencing factors. Achieving optimum conditions for production.

Bioreactor characterization

We perform bioreactor characterizations based on scientifically validated measurements and calculations.

Improved operational efficiency

We help you optimize your existing production systems to increase throughput and minimize downtime.

Performance parameter analysis

We assess and clearly define important performance parameters like oxygen transfer rate, mixing time, power input, heat transfer.

Quality by Design

Aligned with regulatory expectations, our approach incorporates QbD principles to drive in-depth process understanding and consistent product quality from the outset.

Simulation studies

We have extensive expertise in process optimization studies, including process simulation for debottlenecking or optimization, and CFD studies for bioreactor or agitator design.

Enhance production performance. Boost efficiency. Reduce downtime.

Process optimization means more than fine-tuning – it involves improving the manufacturing process by identifying and eliminating potential bottlenecks and increasing productivity, while ensuring the safety, efficacy and quality of the product. Whether implemented during engineering or applied to existing facilities, ZETA’s optimization strategies deliver measurable results: higher yields, fewer disruptions, and smarter, faster production.

Let’s optimize your process.
Together.

Roland Maichin
Corporate Head of Project Development
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Downloads. Process optimization.

White paper bioreactor part 1: Designing bioreactors for consistent scale-up and process validation

Explore how bioreactor design can ensure consistent process conditions from lab to production scale – a critical factor in achieving reliable upstream performance.

White paper bioreactor part 2: Evaluating vvm as a scale-up parameter in bioreactor qualification

Is the commonly used gas flow coefficient (vvm) truly reliable for scale-up and qualification?

White paper bioreactor part 3: Design study of low shear agitators for biopharmaceutical applications

ZETA has conducted a comprehensive study to develop an optimal agitator configuration tailored to low shear systems.

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