Safe and Efficient: Containment Solutions for Highly Potent Active Ingredients

The pharmaceutical industry is increasingly developing highly potent therapies that place special demands on safety and technology. ZETA demonstrates how modern containment engineering ensures the safe and future-proof production of these active ingredients.

EngineeringFabrication & DeliveryModalities Expertise & FacilitiesProcess ExpertiseTechnical Text

Highly potent APIs: opportunities and challenges

Highly potent pharmaceutical ingredients (HPAPIs) offer tremendous therapeutic benefits—especially in oncology and for rare diseases. Their effectiveness at minimal dosages, however, brings significant occupational safety requirements. HPAPIs classified as OEB5 require exposure limits below 1 µg/m³, necessitating highly advanced containment systems.

ZETA addresses these challenges with customized, GMP-compliant solutions that ensure both employee safety and product integrity.

Engineering expertise for the future of drug manufacturing

ZETA supports pharmaceutical manufacturers from early development through to commercial production. Its modular and scalable plant solutions enable maximum flexibility—whether for research units or large-scale facilities.

A best-practice example is the design and implementation of a downstream system for antibody-drug conjugates (ADCs), completed in just 18 months.

With isolator-protected environments, independent operating units, and well-integrated processes, ZETA sets new standards in the safe production of highly potent pharmaceuticals.

Get clarity on complex pharma challenges.

Get in touch Get in touch

Matthias Goriupp

Director Business Line Customised Systems

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