ZETA|Facility Types & Modalities|Blood Plasma Products
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Precision Solutions for Blood Plasma Processing

Streamlining operations in blood plasma fractionation facilities.

Advanced processing systems by ZETA.
Two people in full protective clothing—gowns, gloves, masks, and hair covers—are working in a clean, sterile room. One is pouring material from a large bag into a metal container, while the other is using a control panel on the wall.
Clearnroom view with large filter press
Filter press for filtration of the precipitate.

Transforming blood plasma into life-saving therapies.

Isolating life-saving proteins from human plasma demands more than process control – it requires deep expertise, engineering precision, and unwavering regulatory alignment. ZETA designs and delivers advanced solutions for blood plasma fractionation, supporting manufacturers in producing safe, effective therapies with maximum efficiency and consistency.

Conquering challenges. Prerequisites for excellence.

Batch-to-batch consistency

Proven solutions that maintain critical parameters for reliable, repeatable outcomes across production cycles.

Cost Efficiency

Optimized systems help keep operating costs low while addressing economic and regulatory challenges effectively.

Fractionation efficiency & protein yield

Optimized process design and advanced purification techniques to maximize protein recovery and minimize product loss.

Low-temperature integrity

Reliable cold chain and process controls to preserve protein stability and ensure product quality throughout processing.

Regulatory compliance

Systems and documentation practices designed to meet stringent GMP and evolving global regulatory standards.

Safety, process control & cleanroom operation

Integrated safeguards and controlled environments that ensure product integrity, personnel safety, and contamination-free processing.

End-to-end expertise for plasma processing success.

At ZETA, we provide integrated solutions tailored to the unique challenges of plasma-derived therapies. Our technologies support every stage of plasma processing, helping facilities improve efficiency, ensure compliance, and protect product integrity.

Cryogenic storage solutions

Maintain low-temperature integrity to protect valuable plasma fractions.

Modular cleanroom construction

Rapid deployment of GMP-compliant, contamination-controlled environments.

Process optimization & automation

Maximize protein yields and reduce operational costs through smart design and intelligent automation.

The image shows two pieces of industrial equipment made of shiny metal. One is a control unit with a screen and buttons, including an emergency stop. The other is a large tank with pipes and valves. Both are labeled “ZETA” and used in clean, precise manufacturing settings. A person in full protective gear—suit, gloves, and mask—is using a touchscreen on the wall in a clean, sterile room. The space contains large stainless steel machines, likely used in pharmaceutical or biotech manufacturing. Person in cleanroom clothing operating a touchscreen in cleanroom wall

Maximize your plasma protein recovery.
Unlock the full potential of every batch with optimized fractionation and yield-enhancing technologies.

Johannes Koch
Director Business Line Engineering & Services
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Rethinking plasma fractionation. Unlocking efficiency and quality with ZETA.

Protect product quality

Protect product quality with reliable systems and safeguards.

Reduce operational costs

Reduce operational costs through efficient infrastructure and process design.

Stay compliant

Stay compliant with evolving global regulatory standards.

From beginning to future. Achieving success together with our customers.

Our planning services and systems cover all essential processes in blood plasma processing. With the highest demands on process control and system components, such as those for precipitation, filtration, or thawing, our customers rely on our expertise in media supply and refrigeration technology.

Two person in protective cleanroom clothing, one of them adding something from a bottle via a shovel-like device to a vessel

Major Expansion of Blood Plasma Fractionation Facility

ZETA triples plasma fractionation capacity in Vienna.

Seamless integration, smart cooling solutions, and expert project management: ZETA transforms a courtyard into a high-performance blood plasma facility.

Mobile production skids in cleanroom area, docked on their docking stations on the wall

Multipurpose Pilot Plant for Plasma Processing

High flexibility for over 30 blood plasma-derived products.

Fully automated multiproduct system covering clinical and routine production of new products in addition to pilot production. Allowing production 24/7.

Two people seated at a conference table analyzing a large wall-mounted display showing a detailed, color-coded scheduling chart with multiple rows and timelines.

Holistic Simulation Throughout Facility Design

ZETA delivers ‘First-Time-Right’ integrated engineering using simulation.

A realistic simulation environment is capable of modeling complex batch processes with all their dependencies: utilities, cleaning systems, buffer logistics, WFI generation and more.

ZETA InFlow. Specialized ZETA technology.

Optimize your buffer management with ZETA InFlow, the inline conditioning system for buffer production on demand and at the point of use.

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